Synchronization time in a hyperbolic dynamical system with long-range interactions

We show that the threshold of complete synchronization in a lattice of coupled non-smooth chaotic maps is determined by linear stability along the directions transversal to the synchronization subspace. We examine carefully the sychronization time and show that a inadequate observation of the system evolution leads to wrong results. We present both careful numerical experiments and a rigorous mathematical explanation confirming this fact, allowing for a generalization involving hyperbolic coupled map lattices.Comment: 22 pages (preprint format), 4 figures - accepted for publication in Physica A (June 28, 2010

On Provably Safe and Live Multirobot Coordination With Online Goal Posting

A standing challenge in multirobot systems is to realize safe and efficient motion planning and coordination methods that are capable of accounting for uncertainties and contingencies. The challenge is rendered harder by the fact that robots may be heterogeneous and that their plans may be posted asynchronously. Most existing approaches require constraints on the infrastructure or unrealistic assumptions on robot models. In this article, we propose a centralized, loosely-coupled supervisory controller that overcomes these limitations. The approach responds to newly posed constraints and uncertainties during trajectory execution, ensuring at all times that planned robot trajectories remain kinodynamically feasible, that the fleet is in a safe state, and that there are no deadlocks or livelocks. This is achieved without the need for hand-coded rules, fixed robot priorities, or environment modification. We formally state all relevant properties of robot behavior in the most general terms possible, without assuming particular robot models or environments, and provide both formal and empirical proof that the proposed fleet control algorithms guarantee safety and liveness

Ion transport and heating in simulations of plasma turbulence

The processes of particle diffusion and acceleration are currently being tackled worldwide because of their major implications in astrophysical and laboratory plasma physics. Despite the efforts of the whole community, a comprehensive theoretical description of such phenomena is still missing. In this work, a two-dimensional (2D) version of the Non-Linear Guiding Center (NLGC) theory is derived, in order to describe particle transport in some particular scenarios. The theory is validated with 2.5D kinetic simulations of plasma turbulence. Simulations parameters are chosen so that several scenarios can be described, going from the solar corona to the solar wind and the magnetosheath. Finally, the role of turbulence coherent structures on particle acceleration and energization is investigated. Current sheets are found to be of major importance in this scenario and that there is a scale-resonance interaction between the current sheet size and the particles’ Larmor radii

The role of micronutrients in support of the immune response against viral infections

Viral infections are a leading cause of morbidity and mortality worldwide, and the importance of public health practices including handwashing and vaccinations in reducing their spread is well established. Furthermore, it is well known that proper nutrition can help support optimal immune function, reducing the impact of infections. Several vitamins and trace elements play an important role in supporting the cells of the immune system, thus increasing the resistance to infections. Other nutrients, such as omega-3 fatty acids, help sustain optimal function of the immune system. The main aim of this manuscript is to discuss of the potential role of micronutrients supplementation in supporting immunity, particularly against respiratory virus infections. Literature analysis showed that in vitro and observational studies, and clinical trials, highlight the important role of vitamins A, C, and D, omega-3 fatty acids, and zinc in modulating the immune response. Supplementation with vitamins, omega 3 fatty acids and zinc appears to be a safe and low-cost way to support optimal function of the immune system, with the potential to reduce the risk and consequences of infection, including viral respiratory infections. Supplementation should be in addition to a healthy diet and fall within recommended upper safety limits set by scientific expert bodies. Therefore, implementing an optimal nutrition, with micronutrients and omega-3 fatty acids supplementation, might be a cost-effective, underestimated strategy to help reduce the burden of infectious diseases worldwide, including coronavirus disease 2019 (COVID-19)

Breaking projective chaos synchronization secure communication using filtering and generalized synchronization

This paper describes the security weaknesses of a recently proposed secure communication method based on chaotic masking using projective synchronization of two chaotic systems. We show that the system is insecure and how to break it in two different ways, by high-pass filtering and by generalized synchronization.Comment: 14 pages, 6 figures, latex forma

Treatment of multidrug-resistant and extensively drug-resistant tuberculosis in children: The role of bedaquiline and delamanid

Multidrug-resistant (MDR) tuberculosis (TB) has been emerging at an alarming rate over the last few years. It has been estimated that about 3% of all pediatric TB is MDR, meaning about 30,000 cases each year. Although most children with MDR-TB can be successfully treated, up to five years ago effective treatment was associated with a high incidence of severe adverse effects and patients with extensively drug-resistant (XDR) TB had limited treatment options and no standard regimen. The main objective of this manuscript is to discuss our present knowledge of the management of MDR-and XDR-TB in children, focusing on the characteristics and available evidence on the use of two promising new drugs: bedaquiline and delamanid. PubMed was used to search for all of the studies published up to November 2020 using key words such as “bedaquiline” and “delamanid” and “children” and “multidrug-resistant tuberculosis” and “extensively drug-resistant tuberculosis”. The search was limited to articles published in English and providing evidence-based data. Although data on pediatric population are limited and more studies are needed to confirm the efficacy and safety of bedaquiline and delamanid, their use in children with MDR-TB/XDR-TB appears to have good tolerability and efficacy. However, more evidence on these new anti-TB drugs is needed to better guide their use in children in order to design effective shorter regimens and reduce adverse effects, drug interactions, and therapeutic failure

The LAUE project for broadband gamma-ray focusing lenses

We present the LAUE project devoted to develop an advanced technology for building a high focal length Laue lens for soft gamma--ray astronomy (80-600 keV). The final goal is to develop a focusing optics that can improve the current sensitivity in the above energy band by 2 orders of magnitude.Comment: 7 pages, 6 figures, presented at the SPIE conference on "Optics for EUV, X-ray, and Gamma-ray Astronomy". To be published in the Proceedings of SPIE, vol.8147, 201